Beschreibung
Overview:
Clonality: Polyclonal
Host: Rabbit
Reactivity:Human, Mouse
Applications: WB, ELISA
Storage: -20°C for one year
Concentration: 1 mg/ml
Detailed Information:
The protein encoded by ACE2 (angiotensin I converting enzyme 2)belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of ACE2 suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Antibody Production Information:
The antiserum was produced against synthesized peptide derived from human ACE2. AA range:416-465
Target:
Target: ACE2
Synonyms: ACE2; Angiotensin-converting enzyme 2; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; ACEH; Metalloprotease MPROT15
Supplier: BT-Labs