Actin-Alpha cardiac muscle Polyclonal Antibody

Overview:

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, ELISA

Storage: -20°C for one year

Concentration: 1 mg/ml

Detailed Information:

Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. Actin alpha cardiac muscle 1 encoded by ACTC1 belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

Antibody Production Information:

Synthesized peptide derived from Actin-α cardiac muscle . at AA range: 1-80

Target:

Target: Actin-Alpha cardiac muscle

Synonyms: ACTC1; ACTC; Actin, alpha cardiac muscle 1; Alpha-cardiac actin

Supplier: BT-Labs