Anti-Covid-19 N protein mAb IgG(06FC)

Overview:

Clonality: Monoclonal

Host: Mouse

Reactivity:Covid-19

Applications: WB,ELISA

Isotype: IgG

Storage: -20°C for one year

Concentration: 2mg/ml

Detailed Information:

Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways . Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. COVID-19 antibodies can be produced by a host immune system following exposure to SARS-CoV-2. IgG and IgM antibodies are also known as immunoglobulins IgG and IgM, respectively, and are among the antibody isotypes produced by vertebrate immune systems.

Antibody Production Information:

The recombinant SARS-CoV-2 (2019-nCoV) N Protein

Target:

Target: SARS-CoV-2 (2019-nCoV) N Protein

Synonyms: SARS-CoV-2 Nucleoprotein , 2019-nCoV Nucleoprotein, Covid-19 Nucleoprotein

Supplier: BT-Labs