• 0941 948228
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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

ASC-1 Polyclonal Antibody

ab 295,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: BT-AP00663


Beschreibung

Overview:

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB, IHC-p, IF, ELISA

Storage: -20°C for one year

Concentration: 1 mg/ml


Detailed Information:

TRIP4 (thyroid hormone receptor interactor 4) encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in TRIP4 are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1).


Antibody Production Information:

The antiserum was produced against synthesized peptide derived from human TRIP4. AA range:81-130


Supplier: BT-Labs