Beschreibung
Overview:
Clonality: Polyclonal
Host: Rabbit
Reactivity:Human, Rat
Applications: WB, ELISA
Storage: -20°C for one year
Concentration: 1 mg/ml
Detailed Information:
Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms.
Antibody Production Information:
Synthesized peptide derived from part region of human protein
Target:
Target: CABIN
Synonyms: Calcineurin-binding protein cabin-1 ;Calcineurin inhibitor;CAIN
Supplier: BT-Labs