• 0941 948228
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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

Caspase 9 Monoclonal Antibody(3-20)

ab 295,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: BT-MCA0014


Beschreibung

Overview:

Clonality: Monoclonal

Host: Mouse

Reactivity:Human, Mouse, Rat, chicken

Applications: WB, IHC-p, IF, ICC, IP

Storage: -20°C for one year

Concentration: 1 mg/ml


Detailed Information:

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.


Antibody Production Information:

Synthetic Peptide of Caspase 9


Target:

Target: Caspase-9

Synonyms: CASP9; MCH6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6


Supplier: BT-Labs