• 0941 948228
  • Sichere Bezahlung
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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

CD16 Monoclonal Antibody(Q32)

ab 295,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: BT-MCA0017


Beschreibung

Overview:

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IHC-p, IF

Storage: -20°C for one year

Concentration: 1 mg/ml


Detailed Information:

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.


Antibody Production Information:

Synthetic Peptide of CD16


Target:

Target: CD16

Synonyms: FCGR3A; FCGR3B


Supplier: BT-Labs