Beschreibung
Overview:
Clonality: Polyclonal
Host: Rabbit
Reactivity:Human
Applications: WB, ELISA
Storage: -20°C for one year
Concentration: 1 mg/ml
Detailed Information:
CCR2 encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. CCR2 is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
Antibody Production Information:
The antiserum was produced against synthesized peptide derived from the N-terminal region of human CCR2. AA range:1-50
Target:
Target: CCR2
Synonyms: CCR2; CMKBR2; C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; Monocyte chemoattractant protein 1 receptor; MCP-1-R; CD192
Supplier: BT-Labs