Beschreibung
Overview:
Clonality: Monoclonal
Host: Mouse
Reactivity:Human
Applications: IF, ICC, ELISA
Storage: -20°C for one year
Concentration: 1 mg/ml
Detailed Information:
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Antibody Production Information:
Purified recombinant fragment of human CD3 expressed in E. Coli.
Target:
Target: CD247
Synonyms: CD247; CD3Z; T3Z; TCRZ; T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD antigen CD247
Supplier: BT-Labs