Beschreibung
Overview:
Clonality: Monoclonal
Host: Mouse
Reactivity:Human
Applications: FCM, ELISA
Storage: -20°C for one year
Concentration: 1 mg/ml
Detailed Information:
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Antibody Production Information:
Purified recombinant fragment of human CD4 expressed in E. Coli.
Target:
Target: CD4
Synonyms: CD4; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; CD antigen CD4
Supplier: BT-Labs