Beschreibung
Overview:
Clonality: Monoclonal
Host: Mouse
Reactivity:Human
Applications: IHC-p, IF
Storage: -20°C for one year
Concentration: 1 mg/ml
Detailed Information:
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.
Antibody Production Information:
Synthetic Peptide of CD41
Target:
Target: CD41
Synonyms: ITGA2B; GP2B; ITGAB; Integrin alpha-IIb; GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD41
Supplier: BT-Labs