Beschreibung
Overview:
Clonality: Monoclonal
Host: Mouse
Reactivity:Human, Mouse
Applications: WB, IHC-p, IF, ICC, FCM, ELISA
Storage: -20°C for one year
Concentration: 1 mg/ml
Detailed Information:
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Antibody Production Information:
Purified recombinant fragment of human CD44 (628-699) expressed in E. Coli.
Target:
Target: CD44
Synonyms: CD44; LHR; MDU2; MDU3; MIC4; CD44 antigen; CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycopr
Supplier: BT-Labs