• 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
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  • info@davids-bio.com
  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

CD45 Monoclonal Antibody

ab 380,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: BT-MCA0308


Beschreibung

Overview:

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IHC-p, IF, ELISA

Storage: -20°C for one year

Concentration: 1 mg/ml


Detailed Information:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which enc


Antibody Production Information:

Purified recombinant fragment of CD45 expressed in E. Coli.


Target:

Target: CD45

Synonyms: PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45


Supplier: BT-Labs