Beschreibung
Overview:
Clonality: Monoclonal
Host: Mouse
Reactivity:Human
Applications: IF, ICC, WB, IHC-p
Storage: -20°C for one year
Concentration: 1 mg/ml
Detailed Information:
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Antibody Production Information:
Synthetic Peptide of Cleaved PARP
Target:
Target: PARP1
Synonyms: PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
Supplier: BT-Labs