HP1 alpha(Phospho Ser92) Polyclonal Antibody
ab 295,00 €
Artikelnummer: BT-AP10140
Beschreibung
Overview:
Clonality: Polyclonal
Host: Rabbit
Reactivity:Human, Rat, Mouse
Applications: IHC-p, IF, ELISA
Storage: -20°C for one year
Concentration: 1 mg/ml
Detailed Information:
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Antibody Production Information:
The antiserum was produced against synthesized peptide derived from human HP1 alpha around the phosphorylation site of Ser92. AA range:58-107
Target:
Target: HP1 alpha(Phospho Ser92)
Synonyms: Chromobox protein homolog 5; CBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha
Supplier: BT-Labs