Human Adiponectin, ADP ELISA Kit

Overview:

Target Protein: APM1

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -

Sensitivity: 0.11mg/L

Detection range: 0.2-60mg/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Storage: 2 - 8°C

Assay Time: 1:30 h

Detailed Information:

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

APM1 Information:

UniProt Accession: Q15848

Synonyms: 30 kDa adipocyte complement-related protein;ACRP30;Adipocyte complement-related 30 kDa protein;Adipocyte, C1q and collagen domain-containing protein;Adiponectin;Adipose most abundant gene transcript 1 protein;APM 1;APM1;apM-1;Gelatin-binding protein

References:

• Effect of Curcuma longa on vascular function in native Tamilians with type 2 diabetes mellitus: A randomized, double-blind, parallel arm, placebo-controlled trial
• Journal: Phytother Res. 2019 Jul;33(7):1898-1911.
• Oral α-lipoic acid supplementation in patients with non-alcoholic fatty liver disease: effects on adipokines and liver histology features
• Journal: Food Funct. 2019 Aug 1;10(8):4941-4952
• Association of High Serum Adiponectin with the Risk of Malnutrition and Worse Outcome in Head Trauma Patients; a Cohort study
• Journal: Arch Acad Emerg Med. 2019 Aug 24;7(1):e43.
• Effect of Reduction Mammoplasty on Insulin and Lipid Metabolism in the Postoperative Third month: Compensatory Hip Enlargement
• Journal: Aesthetic Plast Surg. 2023 Apr;47(2):536-543.

Supplier: BT-Labs