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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

Human Cd163 Antigen, CD163 ELISA Kit

ab 495,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: E0246Hu


Beschreibung

Overview:

Target Protein: Cd163 Antigen, CD63

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -


Sensitivity: 0.052ng/ml

Detection range: 0.1-30ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human


Storage: 2 - 8°C

Assay Time: 1:30 h


Detailed Information:

Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.


CD63 Information:

UniProt Accession: P08962

Synonyms: CD 63;CD antigen CD63;CD63;CD63 antigen;Granulophysin;LAMP-3;Lysosomal-associated membrane protein 3;Melanoma-associated antigen ME491;Ocular melanoma-associated antigen;OMA81H;Tetraspanin-30;Tspan-30


Supplier: BT-Labs