Human Cluster of Differentiation 3, CD3 ELISA Kit

Overview:

Target Protein: Cluster of Differentiation 3, EID3

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -

Sensitivity: 0.01ng/ml

Detection range: 0.05-20ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Storage: 2 - 8°C

Assay Time: 1:30 h

Detailed Information:

Tissue-specific component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a repressor of nuclear receptor-dependent transcription possibly by interfering with CREBBP-dependent coactivation. May function as a coinhibitor of other CREBBP/EP300-dependent transcription factors.

EID3 Information:

UniProt Accession: Q8N140

Synonyms: E1A-like inhibitor of differentiation 3;EID 3;EID-1-like inhibitor of differentiation 3;EID3;EID-3;EP300-interacting inhibitor of differentiation 3;Non-SMC element 4 homolog B;Non-structural maintenance of chromosomes element 4 homolog B;NS4EB;

Supplier: BT-Labs