Human Cytochrome P450 2E1, CYP2E1 ELISA Kit

Overview:

Target Protein: Cytochrome P450 2E1, CYP2E1

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -

Sensitivity: 9.54ng/L

Detection range: 20-6000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Storage: 2 - 8°C

Assay Time: 1:30 h

Detailed Information:

A cytochrome P450 monooxygenase involved in the metabolism of fatty acids (PubMed: 10553002, PubMed: 18577768). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) (PubMed: 10553002, PubMed: 18577768). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids (PubMed: 10553002, PubMed: 18577768). May be involved in the oxidative metabolism of xenobiotics (Probable).

CYP2E1 Information:

UniProt Accession: P05181

Synonyms: 4-nitrophenol 2-hydroxylase;CYP2E1;CYPIIE1;Cytochrome P450 2E1;Cytochrome P450-J

Supplier: BT-Labs