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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

Human E-Cadherin, E-CAD ELISA Kit

ab 495,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: E0209Hu


Beschreibung

Overview:

Target Protein: E-Cadherin, CDH1

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -


Sensitivity: 0.52ng/ml

Detection range: 1-300ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human


Storage: 2 - 8°C

Assay Time: 1:30 h


Detailed Information:

Cadherins are calcium-dependent cell adhesion proteins (PubMed: 11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed: 11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. (Microbial infection) Serves as a receptor for Listeria monocytogenes; internalin A (InlA) binds to this protein and promotes uptake of the bacteria.


CDH1 Information:

UniProt Accession: P12830

Synonyms: Cadherin-1;CAM 120/80;CD antigen CD324;CDH 1;CDH1;E-Cad/CTF1;E-Cad/CTF2;E-Cad/CTF3;E-cadherin;Epithelial cadherin;Uvomorulin


Supplier: BT-Labs