Beschreibung
Overview:
Target Protein: Fascin, FSCN1
Size: 48T, 96T
Assay Type: Sandwich
One-Step: -
Sensitivity: 11.47ng/L
Detection range: 20-4500ng/L
Sample type: Serum, plasma, cell culture supernates
Reactive with: Human
Storage: 2 - 8°C
Assay Time: 1:30 h
Detailed Information:
Actin-binding protein that contains 2 major actin binding sites (PubMed: 21685497, PubMed: 23184945). Organizes filamentous actin into parallel bundles (PubMed: 20393565, PubMed: 21685497, PubMed: 23184945). Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers (PubMed: 22155786). Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration (PubMed: 20393565, PubMed: 21685497, PubMed: 23184945). Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF (PubMed: 22155786).
FSCN1 Information:
UniProt Accession: Q16658
Synonyms: 55 kDa actin-bundling protein;Fascin;FSCN 1;FSCN1;p55;Singed-like protein
Supplier: BT-Labs