Human Fatty Acid Binding Protein 5, FABP5 ELISA Kit
ab 495,00 €
Artikelnummer: E1399Hu
Beschreibung
Overview:
Target Protein: Fatty Acid Binding Protein 5, FABP5
Size: 48T, 96T
Assay Type: Sandwich
One-Step: -
Sensitivity: 0.091ng/ml
Detection range: 0.2-60ng/ml
Sample type: Serum, plasma, cell culture supernates
Reactive with: Human
Storage: 2 - 8°C
Assay Time: 1:30 h
Detailed Information:
Intracellular carrier for long-chain fatty acids and related active lipids, such as the endocannabinoid, that regulates the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors (PubMed: 22170058, PubMed: 21395585). Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation (By similarity). May be involved in keratinocyte differentiation (PubMed: 8092987).
FABP5 Information:
UniProt Accession: Q01469
Synonyms: E-FABP;Epidermal-type fatty acid-binding protein;FABP 5;FABP5;Fatty acid-binding protein 5;Fatty acid-binding protein, epidermal;PA-FABP;Psoriasis-associated fatty acid-binding protein homolog
Supplier: BT-Labs