Human Fibroblast Growth Factor-23, FGF-23 ELISA Kit

Overview:

Target Protein: Fibroblast Growth Factor-23, FGF23

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -

Sensitivity: 2.49pg/ml

Detection range: 5-1500pg/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Storage: 2 - 8°C

Assay Time: 1:30 h

Detailed Information:

Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.

FGF23 Information:

UniProt Accession: Q9GZV9

Synonyms: FGF 23;FGF23;FGF-23;Fibroblast growth factor 23;Fibroblast growth factor 23 C-terminal Peptide;Fibroblast growth factor 23 N-terminal Peptide;Phosphatonin;Tumor-derived hypophosphatemia-inducing factor

References:

• Relationships Between Left Ventricular Structure and Function According to Cardiac MRI and Cardiac Biomarkers in End-Stage Renal Disease Journal: Can J Cardiol. 2017 Apr;33(4):501-507.
• Serum sTWEAK and FGF-23 Levels in Hemodialysis and Renal Transplant Patients Journal: Int J Organ Transplant Med. 2017;8(2):110-116.

Supplier: BT-Labs