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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

Human Fibronectin, FN ELISA Kit

ab 495,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: E2002Hu


Beschreibung

Overview:

Target Protein: Fibronectin, FN1

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -


Sensitivity: 1.02ng/ml

Detection range: 2-600ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human


Storage: 2 - 8°C

Assay Time: 1:30 h


Detailed Information:

Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin (PubMed: 3024962, PubMed: 3900070, PubMed: 3593230, PubMed: 7989369). Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape (PubMed: 3024962, PubMed: 3900070, PubMed: 3593230, PubMed: 7989369). Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization (By similarity). Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). [Anastellin]: Binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.


FN1 Information:

UniProt Accession: P02751

Synonyms: Anastellin;CIG;Cold-insoluble globulin;Fibronectin;FN;FN 1;FN1;Ugl-Y1;Ugl-Y2;Ugl-Y3


Supplier: BT-Labs