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  • Sichere Bezahlung
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  • info@davids-bio.com

Human Galectin-3, ELISA Kit

ab 495,00 €

(1 Bausatz/-sätze = 495,00 €)
zzgl. MwSt. zzgl. Versand

Artikelnummer: E1951Hu


Beschreibung

Overview:

Target Protein: Galectin-3, LGALS3

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -


Sensitivity: 2.49pg/ml

Detection range: 5-2000pg/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human


Storage: 2 - 8°C

Assay Time: 1:30 h


Detailed Information:

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.


LGALS3 Information:

UniProt Accession: P17931

Synonyms: 35 kDa lectin;Carbohydrate-binding protein 35;CBP 35;Gal-3;Galactose-specific lectin 3;Galactoside-binding protein;GALBP;Galectin-3;IgE-binding protein;L-31;Laminin-binding protein;Lectin L-29;LGALS 3;LGALS3;Mac-2 antigen


References:


Supplier: BT-Labs