Beschreibung
Overview:
Target Protein: Heparin Cofactor 2, SERPIND1
Size: 48T, 96T
Assay Type: Sandwich
One-Step: -
Sensitivity: 0.31ng/L
Detection range: 0.5-150ng/L
Sample type: Serum, plasma, cell culture supernates
Reactive with: Human
Storage: 2 - 8°C
Assay Time: 1:30 h
Detailed Information:
Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
SERPIND1 Information:
UniProt Accession: P05546
Synonyms: HC-II;Heparin cofactor 2;Heparin cofactor II;HLS2;Protease inhibitor leuserpin-2;Serpin D1;SERPIND 1;SERPIND1
Supplier: BT-Labs