Human Histone Deacetylase 8, HDAC8 ELISA Kit
ab 495,00 €
Artikelnummer: E0988Hu
Beschreibung
Overview:
Target Protein: Histone Deacetylase 8, HDAC8
Size: 48T, 96T
Assay Type: Sandwich
One-Step: -
Sensitivity: 0.055ng/mL
Detection range: 0.1-35ng/mL
Sample type: Serum, plasma, cell culture supernates
Reactive with: Human
Storage: 2 - 8°C
Assay Time: 1:30 h
Detailed Information:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.
HDAC8 Information:
UniProt Accession: Q9BY41
Synonyms: HD8;HDAC 8;HDAC8;Histone deacetylase 8
Supplier: BT-Labs