• 0941 948228
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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

Human Histone Deacetylase 8, HDAC8 ELISA Kit

ab 495,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: E0988Hu


Beschreibung

Overview:

Target Protein: Histone Deacetylase 8, HDAC8

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -


Sensitivity: 0.055ng/mL

Detection range: 0.1-35ng/mL

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human


Storage: 2 - 8°C

Assay Time: 1:30 h


Detailed Information:

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.


HDAC8 Information:

UniProt Accession: Q9BY41

Synonyms: HD8;HDAC 8;HDAC8;Histone deacetylase 8


Supplier: BT-Labs