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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

Human Interleukin 16, IL-16 ELISA Kit

ab 495,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: E0096Hu


Beschreibung

Overview:

Target Protein: Interleukin 16, IL16

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -


Sensitivity: 1.47ng/L

Detection range: 3-900ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human


Storage: 2 - 8°C

Assay Time: 1:30 h


Detailed Information:

Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. [Isoform 1]: may act as a scaffolding protein that anchors ion Channels in the membrane. Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.


IL16 Information:

UniProt Accession: Q14005

Synonyms: IL 16;IL16;IL-16;LCF;Lymphocyte chemoattractant factor;Pro-interleukin-16 Interleukin-16


Supplier: BT-Labs