Human Interleukin 1Β, IL-1B ELISA Kit

Overview:

Target Protein: Interleukin 1 beta (IL1B)

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -

Sensitivity: 10.07pg/mL

Detection range: 20-6000pg/mL

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Storage: 2 - 8°C

Assay Time: 1:30 h

Detailed Information:

Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells (PubMed: 10653850). Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6 (PubMed: 12794819).

IL1B Information:

UniProt Accession: P01584

Synonyms: Catabolin;IL 1B;IL 1beta;IL-1 beta;IL1B;Interleukin-1 beta

References:

• Effect of high amylose resistant starch (HAM‐RS2) supplementation on biomarkers of inflammation and oxidative stress in hemodialysis patients: a randomized clinical trial
• Journal: Hemodial Int. 2018 Oct;22(4):492-500.
• The Relationship between Serum Concentrations of Pro- and Anti-Inflammatory Cytokines and Nutritional Status in Patients with Traumatic Head Injury in the Intensive Care Unit
• Journal: Medicina (Kaunas). 2019 Aug 15;55(8):486.
• Different spexin level in obese vs normal weight children and its relationship with obesity related risk factors
• Journal: Nutr Metab Cardiovasc Dis. 2020 Apr 12;30(4):674-682
• Correlation between serum pro inflammatory cytokines and clinical scores of knee osteoarthritic patients using resveratrol as a supplementary therapy with meloxicam
• Journal: Indian J Pharmacol. 2021 Jul-Aug;53(4):270-277.
• The Potential Predictive Role of Tumour Necrosis Factor-α, Interleukin-1β, and Monocyte Chemoattractant Protein-1 for COVID-19 Patients Survival
• Journal: Infect Drug Resist. 2022 Mar 4;15:821-829.
• Effects of autologous leukocyte-platelet rich fibrin (L-PRF) on the rate of maxillary canine retraction and various biomarkers in gingival crevicular fluid (GCF): A split mouth randomized controlled trial
• Journal: Int Orthod. 2022 Dec;20(4):100681.
• Evaluation of periodontal status and cytokine response in children with familial Mediterranean fever or systemic juvenile idiopathic arthritis
• Journal: Clin Oral Investig. 2023 Mar;27(3):1159-1166.
• Correlation Between IL-8, C-Reactive Proteins (CRP) and Neutrophil to Lymphocyte Ratio (NLR) as Predictor of Mortality in COVID-19 Patients with Diabetes Mellitus Comorbidity
• Journal: Int J Gen Med. 2023 Jun 8;16:2349-2354.
• Oxidative stress, DNA damage, and inflammation in COVID-19 patients
• Journal: North Clin Istanb. 2023 Jun 20;10(3):335-340.
• Urotensin-II, oxidative stress, and inflammation increase in hypertensive and resistant hypertensive patients
• Journal: Clin Exp Hypertens. 2021 Apr 3;43(3):211-216.
• The Relationship Between Cytokine Concentrations and Severity Scoring Index for Crimean-Congo Hemorrhagic Fever
• Journal: Cureus. 2023 Feb 11;15(2):e34882.
• The Clinical and Laboratory Efficacy of HA 330 Treatment Combined with Continuous Renal Replacement Therapy in Septic Shock Patients: A Case Series
• Journal: Blood Purif. 2023;52(2):140-147.

Supplier: BT-Labs