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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

Human Interleukin 21, IL-21 ELISA Kit

ab 495,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: E0057Hu


Beschreibung

Overview:

Target Protein: Interleukin 21, IL21

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -


Sensitivity: 2.46ng/L

Detection range: 5-1500ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human


Storage: 2 - 8°C

Assay Time: 1:30 h


Detailed Information:

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (PubMed: 11081504, PubMed: 15178704). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity).


IL21 Information:

UniProt Accession: Q9HBE4

Synonyms: IL 21;IL21;IL-21;Interleukin-21;Za11


Supplier: BT-Labs