Beschreibung
Overview:
Target Protein: Interleukin 34, IL34
Size: 48T, 96T
Assay Type: Sandwich
One-Step: -
Sensitivity: 0.23ng/L
Detection range: 0.5-150ng/L
Sample type: Serum, plasma, cell culture supernates
Reactive with: Human
Storage: 2 - 8°C
Assay Time: 1:30 h
Detailed Information:
Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
IL34 Information:
UniProt Accession: Q6ZMJ4
Synonyms: IL 34;IL34;IL-34;Interleukin-34
Supplier: BT-Labs