Human Kidney Injury Molecule 1, KIM-1 ELISA Kit

Overview:

Target Protein: Kidney Injury Molecule 1, HAVCR1

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -

Sensitivity: 0.01ng/ml

Detection range: 0.05-10ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Storage: 2 - 8°C

Assay Time: 1:30 h

Detailed Information:

May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). May play a role in kidney injury and repair. (Microbial infection) Acts as a receptor for Hepatitis A virus. (Microbial infection) Acts as a receptor for Ebolavirus and Marburg virus by binding exposed phosphatidyl-serine at the surface of virion membrane (PubMed: 21536871). Serves as a dual receptor for Ebolavirus by also interacting with envelope glycoprotein GP (PubMed: 26487564). (Microbial infection) Acts as a receptor for Dengue virus by binding exposed phosphatidyl-serine at the surface of virion membrane. (Microbial infection) Acts as a receptor for Zika virus by binding to envelope protein E.

HAVCR1 Information:

UniProt Accession: Q96D42

Synonyms: CD antigen CD365;HAVCR 1;HAVCR1;HAVcr-1;Hepatitis A virus cellular receptor 1;Kidney injury molecule 1;KIM-1;T-cell immunoglobulin and mucin domain-containing protein 1;T-cell immunoglobulin mucin receptor 1;T-cell membrane protein 1;TIM;TIM-1;TIMD-1;

References:

• Efficacy of multiple Biomarkers: NGAL, KIM1, Cystatin C and IL18 in predicting pregnancy related acute kidney injury Journal: Pak J Med Sci. 2023 Jan-Feb;39(1):34-40.
• Clinical and subclinical acute kidney injury in children with mild-to-moderate COVID-19 Journal: Pediatr Res. 2023 Feb;93(3):654-660.

Supplier: BT-Labs