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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

Human Lipoprotein Lipase, LPL ELISA Kit

ab 495,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: E1517Hu


Beschreibung

Overview:

Target Protein: Lipoprotein Lipase, LPL

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -


Sensitivity: 5.49pg/ml

Detection range: 10-4000pg/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human


Storage: 2 - 8°C

Assay Time: 1:30 h


Detailed Information:

Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage (PubMed: 8675619, PubMed: 11342582, PubMed: 27578112). Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity (PubMed: 7592706, PubMed: 12032167). Mediates margination of triglyceride-rich lipoprotein particles in capillaries (PubMed: 24726386). Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (PubMed: 11342582, PubMed: 27811232).


LPL Information:

UniProt Accession: P06858

Synonyms: Lipoprotein lipase;LPL;Phospholipase A1


Supplier: BT-Labs