Human Low Density Lipoprotein Receptor, LDLR ELISA Kit

Overview:

Target Protein: Low Density Lipoprotein Receptor, LDLR

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -

Sensitivity: 0.092ng/ml

Detection range: 0.2-70ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Storage: 2 - 8°C

Assay Time: 1:30 h

Detailed Information:

Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. (Microbial infection) Acts as a receptor for hepatitis C virus in hepatocytes, but not through a direct interaction with viral proteins. (Microbial infection) Acts as a receptor for Vesicular stomatitis virus. (Microbial infection) In case of HIV-1 infection, may function as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.

LDLR Information:

UniProt Accession: P01130

Synonyms: LDL receptor;LDLR;Low-density lipoprotein receptor

Supplier: BT-Labs