Human Matrix Metalloproteinase 9, MMP-9 ELISA Kit

Overview:

Target Protein: Matrix Metalloproteinase 9/Gelatinase B, MMP-9

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -

Sensitivity: 15.12ng/L

Detection range: 30-9000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Storage: 2 - 8°C

Assay Time: 1:30 h

Detailed Information:

Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration (PubMed:2551898, PubMed:1480034, PubMed:12879005).

Could play a role in bone osteoclastic resorption (By similarity).

Cleaves KiSS1 at a Gly-|-Leu bond (PubMed:12879005).

Cleaves NINJ1 to generate the Secreted ninjurin-1 form (PubMed:32883094).

Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (PubMed:1480034).

Degrades fibronectin but not laminin or Pz-peptide.

MMP-9 Information:

UniProt Accession: P14780

Synonyms: 67 kDa Matrix Metalloproteinase-9;82 kDa Matrix Metalloproteinase-9];92 kDa gelatinase;92 kDa type IV collagenase;CLG4B;Gelatinase B;GELB;MANDP2;Matrix Metalloproteinase-9;MMP-9

References:

• Probiotic Soy Milk Consumption and Renal Function Among Type 2 Diabetic Patients with Nephropathy: a Randomized Controlled Clinical Trial Journal: Probiotics Antimicrob Proteins. 2019 Mar;11(1):124-132.
• Association between Serum Vitamin D Concentration Status and Matrix Metalloproteinase-9 in Patients Undergoing Elective Percutaneous Coronary Intervention Journal: Iran J Pharm Res. 2020 Fall;19(4):135-142
• Serum galectin-3BP as a novel marker of obesity and metabolic syndrome in Chinese adolescents Journal: BMJ Open Diabetes Res Care. 2021 Apr;9(1):e001894.
• Association of the Gelatinase B/Metalloproteinase 9 (MMP-9) Gene Haplotype in Systemic Lupus Erythematosus (SLE) in the Pediatric Egyptian Population Journal: Children (Basel). 2022 Aug 24;9(9):1271.
• Low-dose rosmarinic acid and thymoquinone accelerate wound healing in retinal pigment epithelial cells Journal: Int Ophthalmol. 2023 Oct;43(10):3811-3821.
• Relationship Between Circulating Serpina3g, Matrix Metalloproteinase-9, and Tissue Inhibitor of Metalloproteinase-1 and -2 with Chronic Obstructive Pulmonary Disease Severity Journal: Biomolecules. 2019 Feb 13;9(2):62.
• The effect of Coenzyme Q10 supplementation on serum levels of lactate, pyruvate, matrix metalloproteinase 9 and nitric oxide in women with migraine. A double blind, placebo, controlled randomized clinical trial Journal: European Journal of Integrative Medicine,Volume 21,2018,Pages 70-76
• Extracellular matrix collagen biomarker levels in patients who underwent pulmonary endarterectomy Journal: Eur J Cardiothorac Surg. 2023 Apr 3;63(4):ezad106.
• Role of serum metalloproteinases 2 and 9 to assess the severity of COVID-19 in pregnant women: a prospective cross-sectional study Journal: Ginekologia Polska, Vol 94, No 8(2023), Pages: 638-644
• MMP-9 and TIMP-1 Levels in Children and Adolescents with Obsessive Compulsive Disorder Journal: Neurochem. J. 17, 143–148 (2023).
• Relationship between interferon-induced transmembrane protein 3 and matrix metalloproteinase-9 gene polymorphisms in patients with hepatocellular carcinoma Journal: Clin Res Hepatol Gastroenterol. 2023 May;47(5):102110.

Supplier: BT-Labs