Human Mitogen-activated Protein Kinase 6, MAPK6 ELISA Kit

Overview:

Target Protein: Mitogen-Activated Protein Kinase 6, MAPK6

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -

Sensitivity: 0.092ng/mL

Detection range: 0.2-60ng/mL

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Storage: 2 - 8°C

Assay Time: 1:30 h

Detailed Information:

Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity).

MAPK6 Information:

UniProt Accession: Q16659

Synonyms: ERK-3;Extracellular signal-regulated kinase 3;MAP kinase 6;MAP kinase isoform p97;MAPK 6;MAPK6;Mitogen-activated protein kinase 6;p97-MAPK

Supplier: BT-Labs