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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

Human Myelin Basic Protein, MBP ELISA Kit

ab 495,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: E1531Hu


Beschreibung

Overview:

Target Protein: Myelin Basic Protein, MBP

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -


Sensitivity: 32.27ng/L

Detection range: 50-6000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human


Storage: 2 - 8°C

Assay Time: 1:30 h


Detailed Information:

The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.


MBP Information:

UniProt Accession: P02686

Synonyms: MBP;Myelin A1 protein;Myelin basic protein;Myelin membrane encephalitogenic protein


Supplier: BT-Labs