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  • info@davids-bio.com

Human Vascular Endothelial Cell Growth Factor A, VEGF-A ELISA Kit

(1 Bausatz/-sätze = 495,00 €)

ab 495,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: E0050Hu


Beschreibung

Overview:

Target Protein: Vascular Endothelial Cell Growth Factor A, VEGFA

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -


Sensitivity: 1.52ng/L

Detection range: 3-900ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human


Storage: 2 - 8°C

Assay Time: 1:30 h


Detailed Information:

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity).


VEGFA Information:

UniProt Accession: P15692

Synonyms: Vascular endothelial growth factor A;Vascular permeability factor;VEGF A;VEGFA;VEGF-A;VPF


References:


Supplier: BT-Labs