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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

Human Visfatin, VISFATIN ELISA Kit

ab 495,00 €

(1 Bausatz/-sätze = 495,00 €)
zzgl. MwSt. zzgl. Versand

Artikelnummer: E0025Hu


Beschreibung

Overview:

Target Protein: Visfatin

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -


Sensitivity: 0.23ng/ml

Detection range: 0.5-100ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human


Storage: 2 - 8°C

Assay Time: 1:30 h


Detailed Information:

Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).


Visfatin Information:

UniProt Accession: P43490

Synonyms: NAmPRTase;Nampt;Nicotinamide phosphoribosyltransferase;Pre-B cell-enhancing factor;Pre-B-cell colony-enhancing factor 1;VISFATIN


References:


Supplier: BT-Labs