Human Visfatin, VISFATIN ELISA Kit

Overview:

Target Protein: Visfatin

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -

Sensitivity: 0.23ng/ml

Detection range: 0.5-100ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Storage: 2 - 8°C

Assay Time: 1:30 h

Detailed Information:

Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).

Visfatin Information:

UniProt Accession: P43490

Synonyms: NAmPRTase;Nampt;Nicotinamide phosphoribosyltransferase;Pre-B cell-enhancing factor;Pre-B-cell colony-enhancing factor 1;VISFATIN

References:

• Effect of intermittent fasting during Ramadan on Visfatin, Adiponectin and tumor necrotizing factor-alpha in healthy Muslim individuals Journal: Journal of Fasting and Health, 5 (2). pp. 50-55.
• Comparison of salivary Visfatin in patients with periodontitis and peri-implantitis in an Iranian population Journal: J Periodontol Implant Dent. 2016;8(2): 37-42.
• Salivary visfatin concentrations in patients with chronic periodontitis Journal: J Periodontol. 2014 Aug;85(8):1081-5.
• Salivary Visfatin Concentration in Response to Non-surgical Periodontal Therapy Journal: J Clin Diagn Res. 2015 Apr;9(4):ZC05-8.
• Significance of Some Non-Invasive Biomarkers in the Early Diagnosis and Staging of Egyptian Breast Cancer Patients Journal: Asian Pac J Cancer Prev. 2020 Nov 1;21(11):3279-3284.
• Measuring visfatin levels in saliva: an alternative approach to gestational diabetes screening Journal: Arch Endocrinol Metab. 2021 Nov 24;65(6):747-751.
• Salivary Visfatin Concentration in Response to Non-surgical Periodontal Therapy. Journal: J Clin Diagn Res, 2015, 9 (4): 05-8
• The effect of l-carnitine supplementation on serum levels of omentin-1, visfatin and SFRP5 and glycemic indices in patients with pemphigus vulgaris: A randomized, double-blind, placebo-controlled clinical trial Journal: Phytother Res. 2020 Apr;34(4):859-866.
• Is periodontal inflamed surface area associated with serum and salivary levels of IL-1β, visfatin, and omentin-1 in overweight/obese patients? Journal: Clin Oral Investig. 2022 Aug;26(8):5351-5358.

Supplier: BT-Labs