• 0941 948228
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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

IGF-IR Monoclonal Antibody

ab 380,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: BT-MCA0100


Beschreibung

Overview:

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, IHC-p, ELISA

Storage: -20°C for one year

Concentration: 1 mg/ml


Detailed Information:

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.


Antibody Production Information:

Purified recombinant fragment of IGF-IR expressed in E. Coli.


Target:

Target: IGF1R

Synonyms: IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221


Supplier: BT-Labs