Beschreibung
Overview:
Clonality: Polyclonal
Host: Rabbit
Reactivity:Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Storage: -20°C for one year
Concentration: 1 mg/ml
Detailed Information:
IL5 encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. Interleukin-5 plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2. This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
Antibody Production Information:
The antiserum was produced against synthesized peptide derived from human IL-5. AA range:43-92
Target:
Target: IL5
Synonyms: IL5; IL 5;; Interleukin-5; IL-5; B-cell differentiation factor I; Eosinophil differentiation factor; T-cell replacing factor; TRF
Supplier: BT-Labs