• 0941 948228
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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

Integrin Beta4 Polyclonal Antibody

ab 295,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: BT-AP04590


Beschreibung

Overview:

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Storage: -20°C for one year

Concentration: 1 mg/ml


Detailed Information:

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. ITGB4 encodes Integrin beta-4, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.


Antibody Production Information:

The antiserum was produced against synthesized peptide derived from the Internal region of human ITGB4. AA range:641-690


Target:

Target: ITGB4

Synonyms: ITGB4; Integrin beta-4; GP150; CD104


Supplier: BT-Labs