Beschreibung
Overview:
Clonality: Polyclonal
Host: Rabbit
Reactivity:Human, Rat, Mouse
Applications: WB, ELISA
Storage: -20°C for one year
Concentration: 1 mg/ml
Detailed Information:
This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.
Antibody Production Information:
Synthesized peptide derived from part region of human protein
Target:
Target: LDHB
Synonyms: L-lactate dehydrogenase B chain ;LDH-B;EC 1.1.1.27;LDH heart subunit;LDH-H;Renal carcinoma antigen NY-REN-46
Supplier: BT-Labs