MLH1 Polyclonal Antibody

Overview:

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IF, ELISA

Storage: -20°C for one year

Concentration: 1 mg/ml

Detailed Information:

MLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E.coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

Antibody Production Information:

The antiserum was produced against synthesized peptide derived from human MLH1. AA range: 441-490

Supplier:

BT-Labs