MSH2 Monoclonal Antibody

Overview:

Clonality: Monoclonal

Host: Mouse

Reactivity: Human,Monkey

Applications: WB, IHC-p, IF, ICC, ELISA

Storage: -20°C for one year

Concentration: 1 mg/ml

Detailed Information:

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Antibody Production Information:

Purified recombinant fragment of human MSH2 expressed in E. Coli.

Supplier:

BT-Labs