MSH2 Polyclonal Antibody

Overview:

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human;Mouse;Rat

Applications: IHC-p, IF, ELISA

Storage: -20°C for one year

Concentration: 1 mg/ml

Detailed Information:

MSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E.coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Antibody Production Information:

The antiserum was produced against synthesized peptide derived from human MSH2. AA range:541-590

Supplier: BT-Labs