Beschreibung
Overview:
Clonality: Polyclonal
Host: Rabbit
Reactivity:Human, Mouse, Monkey
Applications: WB, IHC-p, IF, ELISA
Storage: -20°C for one year
Concentration: 1 mg/ml
Detailed Information:
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of RELA, RELA. Four transcript variants encoding different isoforms have been found for RELA.
Antibody Production Information:
The antiserum was produced against synthesized peptide derived from human NF-kappaB p65. AA range:275-324
Target:
Target: NFKappaB-p65
Synonyms: RELA; NFKB3; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Supplier: BT-Labs