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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

NSE2 Polyclonal Antibody

ab 295,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: BT-AP12036


Beschreibung

Overview:

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: WB, ELISA

Storage: -20°C for one year

Concentration: 1 mg/ml


Detailed Information:

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.,pathway:Protein modification; protein sumoylation.,PTM:Sumoylated, possibly via autosumoylation.,Belongs to the NSE2 family.,Contains 1 SP-RING-type zinc finger.,subunit:Component of the SMC5-SMC6 complex which consists of SMC5, SMC6, NSMCE2/MMS21 and probably NSMCE1.,


Antibody Production Information:

Synthesized peptide derived from part region of human protein


Target:

Target: E3 SUMO-protein ligase NSE2

Synonyms: E3 SUMO-protein ligase NSE2 ;EC 6.3.2.-;MMS21 homolog;hMMS21;Non-structural maintenance of chromosomes element 2 homolog;Non-SMC element 2 homolog


Supplier: BT-Labs