Beschreibung
Overview:
Clonality: Polyclonal
Host: Rabbit
Reactivity:Human, Mouse
Applications: WB, ELISA
Storage: -20°C for one year
Concentration: 1 mg/ml
Detailed Information:
This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.
Antibody Production Information:
Synthesized peptide derived from human protein . at AA range: 100-180
Target:
Target: PAK-6
Synonyms: Serine/threonine-protein kinase PAK 6 ;EC 2.7.11.1;PAK-5;p21-activated kinase 6;PAK-6
Supplier:
BT-Labs