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  • info@davids-bio.com

Rat Brain Derived Neurotrophic Facor, BDNF ELISA Kit

(1 Bausatz/-sätze = 495,00 €)

ab 495,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: E0476Ra


Beschreibung

Overview:

Target Protein: Brain Derived Neurotrophic Facor, BDNF

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -


Sensitivity: 0.01ng/ml

Detection range: 0.05-10ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Rat


Storage: 2 - 8°C

Assay Time: 1:30 h


Detailed Information:

Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability (By similarity). [BDNF precursor form]: Important signaling molecule that activates signaling cascades downstream of NTRK2. Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2. Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD). Binding to NGFR and SORCS2 promotes neuronal apoptosis. Promotes neuronal growth cone collapse.


BDNF Information:

UniProt Accession: P23363

Synonyms: BDNF;BDNF precursor form;Brain-derived neurotrophic factor;ProBDNF


References:


Supplier: BT-Labs